Saturday, August 7, 2021

Janssen COVID-19 Vaccine Effectiveness: What are the side effects of Janssen covid vaccine?

 

Janssen COVID-19 Vaccine Effectiveness
Janssen's COVID-19 Vaccine 









Johnson and Johnson's Janssen COVID-19 Vaccine 


Coronavirus (SARS-COV-2) has infected 202.4 million  in the World and nearly 181.9 million has recovered and nearly 4.29  have died  as of 7 August, 2021. The economic, social, and psychological impact of the pandemic is even more devastating.  And, there is no way or measures to get rid of corona until now . There is no specific medicine for COVID-19 patients. In  such pandemic situation, everyone's eyes are on the vaccine to prevent spreading  SARS-COV-2 infection.

New technology and past years experience of scientists made easy to develop vaccines within a year of pandemic after the first coronavirus discovered in Wuhan, China. It is a scientific miracle itself.
Companies in collaboration with well known medical science institutions used their technology, past year's practice to develop vaccines and tested their vaccines in different environments, different countries . They published date of efficacy (effectiveness) of vaccine after completing third stage clinical trials. More than one dozen of different vaccines have been approved by WHO and concerned countries as of 7 August, 2021. Different generic vaccine have different its effectiveness ranging from 60% to 95 % after its full course.

To prevent spread of virus, to make less severity of disease in case of getting infected, to reduce the number of deaths due to Covid-19, we need vaccines. We have no specific treatment for COVID-19 patients so far. Only one means, measures or way that we have is vaccination as soon as possible.

As we are asking for vaccination against SARS-COV-2, at the same time we are too much worried about effectiveness and side effects of the vaccines. Unnecessary, unproven gossip rumours circulating in the social media and newspaper about vaccine, its effectiveness and side effects made more confusion in our community whether to get vaccinated or not. It is necessary to eliminate such unnecessary rumours from our society before vaccination campaign.
Oxford in collaboration with AstraZeneca developed vaccine Oxford AstraZeneca and Covishield, Pfizer-BioNTech, Moderna, Sinopharma, Sputnik, Sinovac, Janssen, Covaxin, CanSino are some examples of covid-19 vaccines that have been used in  worldwide.
Among them, I described about Janssen covid vaccine, its effectiveness (efficacy)and a little bit about its side effects which is common in all vaccines.

The Janssen COVID-19 vaccine was listed for emergency use by World Health Organization (WHO) on 12 March 2021. The vaccine has been authorized emergency use in more than 29 countries including Europe and USA.

Many people are interested to know about the efficacy, safety and side effects of Johnson and Johnson's Janssen vaccine because they are taking this vaccine during COVID-19 pandemic.

Janssen COVID-19 vaccine is single dose vaccine. It is also called Johnson and Johnson's Janssen COVID-19 vaccine. It was developed by Janssen Biotech Inc, a Janssen pharmaceutical company of Johnson and Johnson. Its generic name is JNJ-78436735 or AD26.COV2.S.
It is viral vector type or Adenovirus vector type vaccine.


Effectiveness of Janssen COVID-19 vaccine:

Janssen COVID-19 Vaccine was 66.3 % effective in clinical trials. So efficacy of the vaccine is 66.3 percent in people who have received the janssen vaccine. Clinical trial of Janssen covid vaccine showed that :

 most protection achieved 2 weeks after getting vaccinated
 high efficacy at preventing hospitalization and death in people due to Covid-19
 no one who got infected with SARS-COV-2 at least 4 weeks after receiving Janssen COVID-19 vaccine had to be hospitalized
 single-shot of Janssen vaccine showed ability to protect from multiple variants of SARS-COV-2
 single-shot Janssen COVID-19 vaccine generated strong and persistent activity against the rapidly spreading Delta variant of SARS-COV-2

Durability of vaccine ie, how long does it work, is under study.

Safety of Janssen COVID-19 Vaccine


On the context of safety of Janssen covid vaccine, data available from both clinical trials and preliminary data from country surveillance programmes on their efficacy and safety showed safe with some common mild side effects. Being safe and high efficacy of vaccine, there have been reports of very rare but serious cases of blood clots (thrombosis) accompanied by low platelet counts (thrombocytopenia). This type of syndrome is called Thrombosis with thrombocytopenia syndrome (TTS). TTS found to  be occurred 3 to 30 days after vaccination with COVID-19 non-replicant adenovirus vector-based vaccines such as Covishield and Janssen.
So it would be better to get tested your blood after you get vaccinated within 4- 20 days.

After a careful scientific reviewing of the available information, Global Advisory Committee on Vaccine Safety (GACVS) has come to conclusion that the benefits of the Johnson and Johnson's Janssen COVID-19 vaccine outweighs the risk of TTS. Janssen COVID-19 vaccine has been considered an important tool to prevent infection and to reduce the deaths due to Covid-19 across the world.

Side effects of Janssen COVID-19 Vaccine

Like other COVID-19 vaccines, Johnson and Johnson's Janssen COVID-19 vaccine can cause mild to moderate short term side effects, such as a low grade fever, tiredness  muscles pain, headache, chill, nausea and redness at the site of injection.  Most of the reactions go away within a few days. More serious and long lasting side effects of Janssen COVID-19 vaccine ,such as  thrombosis with thrombocytopenia syndrome (TTS), are possible but very rare . Except TTS , all other reported side effects to Janssen COVID-19 vaccine have mostly been mild to moderate and short lasting.
Note that one  should not get vaccinated with Janssen COVID-19 vaccine if he/she had a severe allergic reaction to any ingredient of this type of vaccine.

Take one thing in mind that vaccination is a critical tool to help prevent spread of infection, further illness and death and to control the pandemic. So you should get vaccinated with available vaccine in your place as soon as possible.


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